| Round Of 32 | Sweet 16 | Quarter Finals | Semi-Finals | Final | Champion | |
| | Delaware Tribe Scurci - 8 | MS Thunderbolts-Sheffield 2025 - 3 | Turnin2 - Robeson / Long - 3 | BSC Bengals 14U - Briggs - 1 | Atlanta vipers 08 Tamborra | |
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| 11/13/2021 4:30 PM #15 - MT F5 | |
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| Fury 07 8170 - 1 | 11/14/2021 8:30 AM #23 - MT F1 | |
| 11/13/2021 1:30 PM #1 - MT F1 | |
| MS Thunderbolts-Sheffield 2025 - 12 | |
| MS Thunderbolts-Sheffield 2025 - 4 | |
| | Turnin2 - Robeson / Long - 5 | 11/14/2021 10:00 AM #27 - MT F1 | |
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| 11/13/2021 6:00 PM #16 - MT F1 | |
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| | Turnin2 - Robeson / Long - 4 | |
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| Georgia Impact 08 Taylor 8156 - 1 | |
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| | IN Bombers 25/26 - 7 | IN Bombers 25/26 - 1 | 11/14/2021 11:30 AM #29 - MT F1 | |
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| 11/13/2021 6:00 PM #17 - MT F2 | |
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| Lady Dukes 08 - 2 | 11/14/2021 8:30 AM #24 - MT F2 | |
| 11/13/2021 1:30 PM #5 - MT F5 | |
| Firecrackers Medina/Miller - 1 | |
| Firecrackers Medina/Miller - 7 | |
| | Lady Lightning Gold Pedy/Grice - 0 | BSC Bengals 14U - Briggs - 5 | |
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| 11/13/2021 6:00 PM #18 - MT F3 | |
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| BSC Bengals 14U - Briggs - 9 | BSC Bengals 14U - Briggs - 6 | |
| 11/13/2021 3:00 PM #7 - MT F2 | |
| BSC Bengals 14U - Briggs - 7 | |
| SFL Diamond Dusters - de Leon - 3 | |
| | Birmingham Thunderbolts Premier 2026 Thompson - 3 | Atlanta vipers 08 Tamborra - 9 | Atlanta vipers 08 Tamborra - 9 | |
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| 11/13/2021 6:00 PM #19 - MT F4 | |
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| Frost Falcons 07 Adams 5600 - 2 | 11/14/2021 8:30 AM #25 - MT F3 | |
| 11/13/2021 3:00 PM #8 - MT F3 | |
| Atlanta vipers 08 Tamborra - 4 | |
| Atlanta vipers 08 Tamborra - 7 | |
| | Georgia Impact 07 Carnes/Turner - 7 | 11/14/2021 10:00 AM #28 - MT F2 | |
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| 11/13/2021 6:00 PM #20 - MT F5 | |
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| | Georgia Impact 07 Carnes/Turner - 4 | |
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| Mojo 2025 - Nelson - 4 | |
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| | Louisiana Voodoo - Dauthier - 1 | Florida Thunderbolts 07 - 6 | Atlanta vipers 08 Tamborra - 4 | |
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| 11/13/2021 7:30 PM #21 - MT F1 | |
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| Florida Thunderbolts 07 - 7 | 11/14/2021 8:30 AM #26 - MT F4 | |
| 11/13/2021 4:30 PM #12 - MT F2 | |
| Florida Thunderbolts 07 - 2 | |
| VA Glory National Norton - 5 | |
| | EC Bullets 07 Branch - 1 | Florida Thunderbolts 07 - 3 | |
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| 11/13/2021 7:30 PM #22 - MT F2 | |
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| Hanover Hornets 2025 National - 4 | Hanover Hornets 2025 National - 0 | |
| 11/13/2021 4:30 PM #14 - MT F4 | |
| Hanover Hornets 2025 National - 7 | |
| RI Thunder National - Lotti - 2 | |