| Round Of 64 | Round Of 32 | Sweet 16 | Quarter Finals | Semi-Finals | Final | |
| | LLG Pedy/McGowan - 0 | Mojo 2022/23 Henson 7983 - 3 | Hanover Hornets 2022 National 4984 - 6 | Hanover Hornets 2022 National 4984 - 3 | Georgia Impact Premier Caymol 7569 | |
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| 11/13/2021 6:30 PM #367 - SQ F1 | |
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| Mojo 2022/23 Henson 7983 - 7 | 11/14/2021 8:30 AM #375 - TC F3 | |
| 11/13/2021 3:10 PM #359 - SQ F1 | |
| Mojo 2022/23 Henson 7983 - 3 | |
| NC Challengers Premier Renzi - 1 | |
| | Atlanta Vipers Hutto 4127 - 2 | 11/14/2021 11:50 AM #379 - TC F3 | |
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| 11/13/2021 6:30 PM #368 - SQ F2 | |
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| Hanover Hornets 2022 National 4984 - 4 | Hanover Hornets 2022 National 4984 - 5 | |
| 11/13/2021 3:10 PM #360 - SQ F2 | |
| Hanover Hornets 2022 National 4984 - 3 | |
| SCT NATIONALS - 3 | |
| | Firecrackers 18 Gold - 2 | BanditsElitePremier-Simpson - 10 | 11/14/2021 1:30 PM #381 - TC F2 | |
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| 11/13/2021 6:30 PM #369 - SQ F3 | |
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| BanditsElitePremier-Simpson - 7 | 11/14/2021 8:30 AM #376 - TC F4 | |
| 11/13/2021 3:10 PM #361 - SQ F3 | |
| BanditsElitePremier-Simpson - 5 | |
| Tennessee Impact - Gainer 4561 - 1 | |
| | Tennessee Mojo 2022 7771 - 4 | BanditsElitePremier-Simpson - 4 | |
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| 11/13/2021 6:30 PM #370 - SQ F4 | |
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| South Jersey Mystics Gold Jackson 5264 - 7 | South Jersey Mystics Gold Jackson 5264 - 5 | |
| 11/13/2021 3:10 PM #362 - SQ F4 | |
| South Jersey Mystics Gold Jackson 5264 - 5 | |
| TNT Maryland (TNT MD) - 0 | |
| | D1VISION Softball 18U Platinum - 2 | Georgia Impact Premier Caymol 7569 - 4 | Georgia Impact Premier Caymol 7569 - 6 | 11/14/2021 3:10 PM #382 - TC F3 | |
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| 11/13/2021 8:10 PM #371 - SQ F1 | |
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| Georgia Impact Premier Caymol 7569 - 3 | 11/14/2021 8:30 AM #377 - TC F5 | |
| 11/13/2021 4:50 PM #363 - SQ F1 | |
| Georgia Impact Premier Caymol 7569 - 4 | |
| Delaware Cobras National 4377 - 2 | |
| | Georgia Impact 04 / Deyton 4436 - 1 | 11/14/2021 11:50 AM #380 - TC F4 | |
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| 11/13/2021 8:10 PM #372 - SQ F2 | |
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| Atlanta Vipers - Palazzo 4149 - 5 | Atlanta Vipers - Palazzo 4149 - 2 | |
| 11/13/2021 4:50 PM #364 - SQ F2 | |
| Atlanta Vipers - Palazzo 4149 - 3 | |
| Lady Dukes National 2022/2023 -Rabitsch 4962 - 3 | |
| | Vexus 18u Martin 6690 - 1 | Top Gun National II - 4 | Georgia Impact Premier Caymol 7569 - 6 | |
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| 11/13/2021 8:10 PM #373 - SQ F3 | |
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| Team Ohio Red - 4 | 11/14/2021 10:10 AM #378 - TC F5 | |
| 11/13/2021 4:50 PM #365 - SQ F3 | |
| Top Gun National II - 2 | |
| Top Gun National II - 11 | |
| | Team Virginia Mizuno - Harrington - 4 | Top Gun National II - 3 | |
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| 11/13/2021 8:10 PM #374 - SQ F4 | |
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| Marucci Patriots 18U Gold 4476 - 6 | Team Virginia Mizuno - Harrington - 3 | |
| 11/13/2021 4:50 PM #366 - SQ F4 | |
| Marucci Patriots 18U Gold 4476 - 0 | |
| Capital District Fusion - 0 | |
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